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Title
Interactions of copper with temperature and oxygen depletion stress on reactive oxygen species (ROS) homeostasis in heart mitochondria
Date
2021
Author
Isei, Michael O.
Genre
Dissertation/Thesis
Abstract
Mitochondria are a common target of multiple abiotic stressors that alter reactive oxygen species (ROS) metabolism. Thus, assessing the effects of...
Thesis Supervisor
Kamunde, Collins
Publisher
University of Prince Edward Island
Publication Status
PUBLISHED
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Title
Effects of copper and temperature on heart mitochondrial hydrogen peroxide production
Source
Free Radical Biology and Medicine
Date
2020
Author
Isei, Michael O.; Kamunde, Collins
Genre
Journal Article
Volume
147
Start Page
114
DOI
10.1016/j.freeradbiomed.2019.12.006
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Bookmarks:
Title
Temperature rise and copper exposure reduce heart mitochondrial reactive oxygen species scavenging capacity
Source
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
Date
2021
Author
Isei, Michael O.; Stevens, Don; Kamunde, Collins
Genre
Journal Article
Abstract
Mitochondria produce and scavenge reactive oxygen species (ROS); however, whether oxidative distress due to exogenous stress arises from excessive...
Start Page
108999
DOI
10.1016/j.cbpc.2021.108999
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Title
Copper modulates heart mitochondrial H2O2 emission differently during fatty acid and pyruvate oxidation
Source
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
Date
2022
Author
Isei, Michael O.; Stevens, Don; Kamunde, Collins
Genre
Journal Article
Abstract
Although the preferred cardiac metabolic fuels are fatty acids, glucose metabolism also plays an important role. However, irrespective of substrate...
Volume
254
Start Page
109267
DOI
10.1016/j.cbpc.2022.109267
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Bookmarks:
Title
Anoxia-reoxygenation alters H2O2 efflux and sensitivity of redox centers to copper in heart mitochondria
Source
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
Date
2021
Author
Isei, Michael O.; Chinnappareddy, Nirmala; Stevens, Don; Kamunde, Collins
Genre
Journal Article
Abstract
Mitochondrial reactive oxygen species (ROS) have been implicated in organ damage caused by environmental stressors, prompting studies on the effect...
Volume
248
Start Page
109111
DOI
10.1016/j.cbpc.2021.109111