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Title
Investigating the function of the Schwann cells in diabetic wound healing
Source
2021 UPEI Graduate Studies and Research Conference
Date
2021
Author
Mahbub Rahman, Shahreen; Johnston, Adam; Murphy, Patrick; Wang, Yanwen
Genre
Abstract
Abstract
Type-2 Diabetes Mellitus (T2DM) is a multifactorial disorder that occurs due to lack of insulin & hyperglycemia. My focus is relating two major...
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Title
A qualitative proteome investigation of the sediment portion of human urine
Subtitle
Implications in the biomarker discovery process
Source
PROTEOMICS - Clinical Applications
Date
2008
Author
Mataija-Botelho, Diane; Murphy, Patrick; Pinto, Devanand M.; MacLellan, Dawn L.; Langlois, Chantale; Doucette, Alan A.
Genre
Journal Article
Abstract
Inherent to the biomarker discovery process is a comparative analysis of physiological states. It is therefore critical that the proteome detection...
Volume
3
Issue
1
Start Page
95
DOI
10.1002/prca.200800019
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Title
Autophagic homeostasis is required for the pluripotency of cancer stem cells
Source
Autophagy
Date
2017
Author
Sharif, Tanveer; Martell, Emma; Dai, Cathleen; Kennedy, Barry E.; Murphy, Patrick; Clements, Derek R.; Kim, Youra; Lee, Patrick W. K.; Gujar, Shashi A.
Genre
Journal Article
Abstract
Pluripotency is an important feature of cancer stem cells (CSCs) that contributes to self-renewal and chemoresistance. The maintenance of...
Volume
13
Issue
2
Start Page
264
DOI
10.1080/15548627.2016.1260808
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Title
TAp73 modifies metabolism and positively regulates growth of cancer stem–like cells in a redox-sensitive manner
Source
Clinical Cancer Research
Date
2019
Author
Sharif, Tanveer; Dai, Cathleen; Martell, Emma; Ghassemi-Rad, Mohammad Saleh; Hanes, Mark Robert; Murphy, Patrick J.; Kennedy, Barry E.; Venugopal, Chitra; Subapanditha, Minomi; Giacomantonio, Carman A.; Marcato, Paola; Singh, Sheila K.; Gujar, Shashi
Genre
Journal Article
Abstract
Purpose: Stem-like cancer cells, with characteristic self-renewal abilities, remain highly refractory to various clinical interventions. As such,...
Volume
25
Issue
6
Start Page
2001
DOI
10.1158/1078-0432.CCR-17-3177
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Title
HDAC6 differentially regulates autophagy in stem-like versus differentiated cancer cells
Source
Autophagy
Date
2019
Author
Sharif, Tanveer; Martell, Emma; Dai, Cathleen; Ghassemi-Rad, Mohammad Saleh; Hanes, Mark Robert; Murphy, Patrick J.; Margam, Nandini N.; Parmar, Hirendrasinh B.; Giacomantonio, Carman A.; Duncan, Roy; Lee, Patrick W.K.; Gujar, Shashi
Genre
Journal Article
Abstract
Cancer stem-like cells (CSCs), a small population of pluripotent cells residing within heterogeneous tumor mass, remain highly resistant to various...
Volume
15
Issue
4
Start Page
686
DOI
10.1080/15548627.2018.1548547