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Title: Spatially-resolved probing of biological phantoms by point-radiance spectroscopy
Source: Proc. of SPIE
Date: 2011
Author: Grabtchak, Serge; Palmer, Tyler J.; Whelan, William M.
Genre: Journal Article
Abstract: Interstitial fiber-optic based strategies for therapy monitoring and assessment rely on detecting treatment-induced changes in the light...
Volume: 7894
Issue: 78940A
DOI: 10.1117/12.874042




Bookmarks:

Title: Optoacoustic imaging in a murine prostate cancer model
Date: 2010
Author: Patterson, Michelle P.; Riley, Christopher B.; Kolius, Michael C. Whelan;William M.




Bookmarks:

Title: Study of laser-induced thermoelastic deformation of native and coagulated ex-vivo bovine liver tissues for estimating their optical and thermomechanical properties
Source: Journal of Biomedical Optics
Date: 2010
Author: Soroushian, Behrouz; Whelan, William M.; Kolios, Michael C.
Genre: Journal Article
Volume: 15
Issue: 6
Start Page: 065002
DOI: 10.1117/1.3517455




Bookmarks:

Title: Study of laser-induced thermoelastic deformation of native and coagulated ex-vivobovine liver tissues for estimating their optical and thermomechanical properties
Source: Journal of Biomedical Optics
Date: 2010
Author: Soroushiam, Behrouz; Whelan, William M; Kolios, Michael C
Genre: Journal Article
Volume: 15
Issue: 6
Start Page: 065002




Bookmarks:

Title: Assessment of thermal coagulation in ex-vivotissues using Raman spectroscopy
Source: Journal of Biomedical Optics
Date: 2010
Author: Rodrigues, Matthew; Weersink, Robert A.; Whelan, William M.
Genre: Journal Article
Volume: 15
Issue: 6
Start Page: 068001




Bookmarks:

Title: Interstitial point radiance spectroscopy of turbid media
Source: Journal of Applied Physics
Date: 2009
Author: Chin, Lee C. L.; Lloyd, Brendan; Whelan, William M.; Vitkin, I. A.
Genre: Journal Article
Volume: 105
Issue: 10
Start Page: 102025
DOI: 10.1063/1.3116132




Bookmarks:

Title: Frequency domain photothermoacoustic signal amplitude dependence on the optical properties of water
Subtitle: turbid polyvinyl chloride-plastisol system
Source: Applied Optics
Date: 2008
Author: Spirou, Gloria M.; Mandelis, Andreas; Vitkin, I. Alex; Whelan, William M.
Genre: Journal Article
Abstract: Photoacoustic (more precisely, photothermoacoustic) signals generated by the absorption of photons can be related to the incident laser fluence...
Volume: 47
Issue: 14
Start Page: 2564




Bookmarks:

Title: A calibration technique for frequency domain photothermoacoustics
Source: European Physical Journal-Special Topics
Date: 2008
Author: Spirou, G. M.; Mandelis, A.; Vitkin, I. A.; Whelan, William M.
Genre: Journal Article
Abstract: Photoacoustic (or more precisely, photothermoacoustic) signals are generated by the absorption of photons, expressed as acoustic waves, and can be...
Volume: 153
Start Page: 491
DOI: 10.1140/epjst/e2008-00492-6




Bookmarks:

Title: Perturbative diffusion theory formalism for interpreting temporal light intensity changes during laser interstitial thermal therapy
Source: Physics in Medicine and Biology
Date: 2007
Author: Chin, Lee C. L.; Whelan, William M.; Vitkin, I. Alex
Genre: Journal Article
Abstract: In an effort to understand dynamic optical changes during laser interstitial thermal therapy ( LITT), we utilize the perturbative solution of the...
Volume: 52
Issue: 6
Start Page: 1659
DOI: 10.1088/0031-9155/52/6/008




Bookmarks:

Title: Determination of the optical properties of turbid media using relative interstitial radiance measurements
Subtitle: Monte Carlo study, experimental validation, and sensitivity analysis
Source: Journal of Biomedical Optics
Date: 2007
Author: Chin, Lee C. L.; Worthington, Arthur E.; Whelan, William M.; Vitkin, I. Alex
Genre: Journal Article
Abstract: Interstitial quantification of the optical properties of tissue is important in biomedicine for both treatment planning of minimally invasive laser...
Volume: 12
Issue: 6
Start Page: 064027
DOI: 10.1117/1.2821406




Bookmarks:

Title: Information content of point radiance measurements in turbid media
Subtitle: implications for interstitial optical property quantification
Source: Applied Optics
Date: 2006
Author: Chin, L. C. L.; Whelan, William M.; Vitkin, I. A.
Genre: Journal Article
Abstract: Motivated by a recent report by Dickey et al. [Phys. Med. Biol. 46, 2359 (2001)], who demonstrated optical property retrieval by using relative...
Volume: 45
Issue: 9
Start Page: 2101




Bookmarks:

Title: Characterization of measurement artefacts in fluoroptic temperature sensors
Subtitle: implications for laser thermal therapy at 810 nm
Source: Lasers in Surgery and Medicine
Date: 2005
Author: Davidson, S. R. H.; Vitkin, I. A.; Sherar, M. D.; Whelan, William M.
Genre: Journal Article
Abstract: Background and Objectives: Fluoroptic sensors are used to measure interstitial temperatures but their utility for monitoring laser interstitial...
Volume: 36
Issue: 4
Start Page: 297




Bookmarks:

Title: A novel strategy for monitoring laser thermal therapy based on changes in optothermal properties of heated tissues
Source: International Journal of Thermophysics
Date: 2005
Author: Whelan, William M.; Davidson, S. R. H.; Chin, L. C. L.; Vitkin, I. A.
Genre: Journal Article
Abstract: Laser thermal therapy uses near-infrared optical energy to heat and thereby treat diseased tissues such as solid tumors. A method to monitor the...
Volume: 26
Issue: 1
Start Page: 233




Bookmarks:

Title: Optical and acoustic properties at 1064 nm of polyvinyl chloride-plastisol for use as a tissue phantom in biomedical optoacoustics
Source: Physics in Medicine and Biology
Date: 2005
Author: Spirou, G. M.; Oraevsky, A. A.; Vitkin, I. A.; Whelan, William M.
Genre: Journal Article
Abstract: A novel optoacoustic phantom made of polyvinyl chloride-plastisol (PVCP) for optoacoustic studies is described. The optical and acoustic properties...
Volume: 50
Issue: 14
Start Page: N141
DOI: 10.1088/0031-9155/50/14/N01



Full Text
Bookmarks:

Title: Laser photothermoacoustic heterodyned lock-in depth profilometry in turbid tissue phantoms
Source: Physical Review E
Date: 2005
Author: Fan, Y.; Mandelis, A.; Spirou, G.; Vitkin, I. A.; Whelan, William M.
Genre: Journal Article
Abstract: Frequency-domain correlation and spectral analysis photothermoacoustic (FD-PTA) imaging is a promising new technique, which is being developed to...
Volume: 72
Issue: 5
Start Page: 051908
DOI: 10.1103/PhysRevE.72.051908
Publication Status: NO_OBJ




Bookmarks:

Title: Radiance-based monitoring of the extent of tissue coagulation during laser interstitial thermal therapy
Source: Optics Letters
Date: 2004
Author: Chin, L. C. L.; Wilson, B. C.; Whelan, William M.; Vitkin, I. A.
Genre: Journal Article
Abstract: Optical monitoring relates the dynamic changes in measured light intensity to the extent of treatment-induced coagulation that occurs during laser...
Volume: 29
Issue: 9
Start Page: 959




Bookmarks:

Title: Models and measurements of light intensity changes during laser interstitial thermal therapy
Subtitle: implications for optical monitoring of the coagulation boundary location
Source: Physics in Medicine and Biology
Date: 2003
Author: Chin, L. C. L.; Whelan, William M.; Vitkin, I. A.
Genre: Journal Article
Abstract: We have developed a multi-region spherical Monte Carlo (MC) model to simulate the dynamic changes in light intensity measured during laser...
Volume: 48
Issue: 4
Start Page: 543




Bookmarks:

Title: Optical method using fluence or radiance measurements to monitor thermal therapy
Source: Review of Scientific Instruments
Date: 2003
Author: Chin, L.; Pop, M.; Whelan, William M.; Sherar, M.; Vitkin, A.
Genre: Journal Article
Abstract: We present data from a two-region (coagulated and native tissue) Monte Carlo simulation in spherical geometry to assess the feasibility of using...
Volume: 74
Issue: 1
Start Page: 393
DOI: 10.1063/1.1519681




Bookmarks:

Title: Optical monitoring of interstitial thermal therapy
Source: Review of Scientific Instruments
Date: 2003
Author: Chin, L. C.; Pop, M.; Whelan, W. M.; Sherar, M. D.; Vitkin, I. A.
Genre: Journal Article
Volume: 74
Start Page: 393




Bookmarks:

Title: Changes in relative light fluence measured during laser heating
Subtitle: implications for optical monitoring and modelling of interstitial laser photocoagulation
Source: Physics in Medicine and Biology
Date: 2001
Author: Chin, L. C. L.; Whelan, William M.; Sherar, M. D.; Vitkin, I. A.
Genre: Journal Article
Abstract: Dynamic changes in internal light fluence were measured during interstitial laser heating of tissue phantoms and ex vivo bovine liver. In albumen...
Volume: 46
Issue: 9
Start Page: 2407

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