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Title
Studies on natural products from select woody plants
Date
2018
Author
Stetson, Colin R.
Genre
Dissertation/Thesis
Abstract
Nannyberry is a plant species located in the northeastern USA and in southern Canada ranging from New Brunswick to southeastern Saskatchewan. The...
Thesis Supervisor
McCallum, Jason; Hurta, Robert
Publisher
University of Prince Edward Island
Publication Status
PUBLISHED
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Title
Magnolol affects cellular proliferation, polyamine biosynthesis and catabolism-linked protein expression and associated cellular signaling pathways in human prostate cancer cells in vitro
Source
Functional Foods in Health and Disease
Date
2015
Author
McKeown, Brendan T.; Hurta, Robert A. R.
Genre
Journal Article
Abstract
Background: Prostate cancer is the most commonly diagnosed form of cancer in men in Canada and the United States. Both genetic and environmental...
Volume
5
Issue
1
Start Page
17
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Title
Ursolic acid mediated inhibition of human prostate cancer cell growth in vitro involves alterations in cell cycle related protein expression
Source
FASEB Journal
Date
2015
Author
Hurta, Robert; Kim, Joseph; Catalli, Adriana; Neto, Catherine
Genre
Conference Abstract
Abstract
Ursolic acid is a constituent of the American cranberry (Vaccinium macrocarpon) and other Vaccinium fruit found primarily in the peel. In this...
Volume
29
Issue
1 Supplement
Start Page
884.5
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Title
Lowbush blueberry component Pterostilbene inhibits the matrix metalloproteinase and the urokinase signaling systems in human prostate cancer cells via alterations in cellular signal transduction pathways
Source
FASEB Journal
Date
2015
Author
Stetson, Colin
Genre
Conference Abstract
Volume
29
Issue
1
Start Page
894.1
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Title
Magnolol affects cellular growth and proliferation in human prostate cancer cells in vitro
Date
2015
Author
McKeown, Brendan Timothy
Genre
Dissertation/Thesis
Abstract
Prostate cancer is the most commonly diagnosed form of cancer in men in Canada and the United States. Both genetic and environmental factors...
Thesis Supervisor
Hurta, Robert
Publisher
University of Prince Edward Island
Publication Status
PUBLISHED
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Title
Magnolol affects expression of IGF-1 and associated binding proteins in human prostate cancer cells in vitro
Source
Anticancer Research
Date
2014
Author
McKeown, Brendan T.; Hurta, Robert A. R.
Genre
Journal Article
Abstract
This study investigated the effects of magnolol, a compound from Magnolia officinalis, on the behavior of LNCaP and PC3 human prostate cancer cells...
Volume
34
Issue
11
Start Page
6333
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Title
Flavonol-enriched fraction from Vaccinium macrocarpon fruit inhibits matrix metalloproteinase-2, matrix metalloproteinase-9 and urokinase-type plasminogen activator expression in human prostate cancer cells in vitro
Source
Functional Foods in Health and Disease
Date
2014
Author
MacPhee, James; Stetson, Colin R.; Elwood, Benjamin W.; Patel, Kunal; McCallum, Jason; Neto, Catherine; Hurta, Robert A.R.
Genre
Journal Article
Abstract
Background: Prostate cancer, amongst other cancer types has a genetic and environmental component, which can contribute to prostate cancer...
Volume
4
Issue
11
Start Page
474
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Title
Magnolol causes alterations in the cell cycle in androgen insensitive human prostate cancer cells in vitro by affecting expression of key cell cycle regulatory proteins
Source
Nutrition and Cancer
Date
2014
Author
McKeown, Brendan T.; McDougall, Luke; Catalli, Adriana; Hurta, Robert A. R.
Genre
Journal Article
Abstract
Prostate cancer, one of the most common cancers in the Western world, affects many men worldwide. This study investigated the effects of magnolol,...
Volume
66
Issue
7
Start Page
1154
DOI
10.1080/01635581.2014.951736
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Title
Proanthocyanidins from the American cranberry (Vaccinium macrocarpon) induce cell cycle alterations in DU145 human prostate cancer cells in vitro by affecting the expression of cell cycle-associated proteins
Source
Functional Foods in Health and Disease
Date
2014
Author
Kim, Joseph; McKeown, Brendan; Jahic, Haris; Patel, Kunal; Catalli, Adriana; Kulka, Marianna; Neto, Catherine; Hurta, Robert
Genre
Journal Article
Abstract
Background: Prostate cancer is one of the most common cancers in the world. There are genetic and environmental factors that can potentially impact...
Volume
4
Issue
4
Start Page
130
DOI
10.31989/ffhd.v4i4.20
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Title
American cranberry (Vaccinium macrocarpon) extract affects human prostate cancer cell growth via cell cycle arrest by modulating expression of cell cycle regulators
Source
Food & Function
Date
2012
Author
Deziel, B.; MacPhee, J.; Patel, K.; Catalli, A.; Kulka, M.; Neto, C.; Gottschall-Pass, K.; Hurta, R.
Genre
Journal Article
Abstract
Prostate cancer is one of the most common cancers in the world, and its prevalence is expected to increase appreciably in the coming decades. As...
Volume
3
Issue
5
Start Page
556
DOI
10.1039/C2FO10145A
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Title
Ursolic acid and its esters: Occurrence in cranberries and other Vaccinium fruit and effects on matrix metalloproteinase activity in DU145 prostate tumor cells
Source
Journal of the Science of Food and Agriculture
Date
2011
Author
Kondo, Miwako; MacKinnon, Shawna L; Craft, Cheryl C; Matchett, Michael D; Hurta, Robert A R; Neto, Catherine C
Genre
Journal Article
Volume
91
Issue
5
Start Page
789
DOI
10.1002/jsfa.4330
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Title
Alterations in the expression of cancer associated mediators in H-ras transformed murine fibroblast cells
Date
2011
Author
Francis, Edward Joesph
Genre
Dissertation/Thesis
Abstract
The progression of cancer is characterized by the alteration in key cancer associated activities. This study investigates the expression of...
Thesis Supervisor
Hurta, Robert
ISBN
9780494822494
Publisher
University of Prince Edward Island
Full Text
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Title
The effects of cranberry phytochemicals on the behaviour of prostate cancer In vitro and In vivo
Date
2011
Author
Deziel, Robert Andrew
Genre
Dissertation/Thesis
Abstract
With an estimated 24,600 cases, prostate cancer is one of the most prevalent cancers in Canada, and evidence suggests that the development of...
Thesis Supervisor
Hurta, Robert; Gottschall-Pass, Katherine
ISBN
9780494822647
Publisher
University of Prince Edward Island
Full Text
Bookmarks:
Title
Compounds of Vaccinium macrocarpon inhibit DU145 human prostate cancer cells
Date
2011
Author
Scott, Bradley Edwin
Genre
Dissertation/Thesis
Abstract
Prostate cancer is the second most prevalent cancer in North American males. A series of in vitro studies were conducted to examine the effect of...
Thesis Supervisor
Hurta, Robert
ISBN
9780494822562
Publisher
University of Prince Edward Island
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Bookmarks:
Title
Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) inhibit matrix metalloproteinase-2 and matrix metalloproteinase-9 activity in human prostate cancer cells via alterations in multiple cellular signalling pathways
Source
Journal of Cellular Biochemistry
Date
2010
Author
Deziel, Bob A.; Patel, Kunal; Neto, Catherine; Gottschall-Pass, Katherine; Hurta, Robert A. R.
Genre
Journal Article
Abstract
Prostate cancer is one of the most common cancers in the Western world, and it is believed that an individual's diet affects his risk of...
Volume
111
Issue
3
Start Page
742
DOI
10.1002/jcb.22761
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Title
Cranberry (Vaccinium macrocarpon) extract reduces tumour necrosis factor alpha-induced expression of cyclooxygenase-2 and inducible nitric oxide synthase in vascular smooth muscle cells
Source
FASEB Journal
Date
2007
Author
MacDougall, Colleen; Amoroso, Jon; Neto, Catherine; Gottschall-Pass, Katherine; Hurta, Robert
Genre
Conference Abstract
Abstract
Natural 'bioactive' factors have the ability to attenuate atherogenesis in in vitro and in vivo models. The effects of cranberry on the...
Volume
21
Issue
5
Start Page
A249
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Title
Oncostatin M-mediated regulation of matrix metalloproteinases and associated mediators of MMPs' expression in H-ras transformed fibroblasts
Source
FASEB Journal
Date
2007
Author
Francis, Edward Joseph; Hurta, Robert
Genre
Conference Abstract
Abstract
Oncostatin M (OSM) is a growth and differentiation factor which has been shown to exert both stimulatory and inhibitory effects on tissue invasion...
Volume
21
Issue
5
Start Page
A278
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Title
Cranberry (Vaccinium macrocarpon) flavonoids inhibit matrix metalloproteinases (MMPs) in human prostate cancer cells
Source
FASEB Journal
Date
2007
Author
MacLean, Malcolm Adam; Matchett, Michael David; Amoroso, Jon; Neto, Catherine; Hurta, Robert
Genre
Conference Abstract
Abstract
Blueberry (Vaccinium angustifolium) flavonoid-containing fractions have been shown to inhibit MMP activity (MMP-2/-9) in DU145 prostate cancer...
Volume
21
Issue
6
Start Page
A1000
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Bookmarks:
Title
Inhibition of matrix metalloproteinase activity in DU145 human prostate cancer cells by flavonoids from lowbush blueberry (Vaccinium angustifolium)
Subtitle
possible roles for protein kinase C and mitogen-activated protein-kinase-mediated events
Source
The Journal of Nutritional Biochemistry
Date
2006
Author
Matchett, M. D.; MacKinnon, S. L.; Sweeney-Nixon, Marva I.; Gottschall-Pass, Katherine T.; Hurta, Robert A. R.
Genre
Journal Article
Abstract
Regulation of the matrix metalloproteinases (MMPs) is crucial to regulate extracellular matrix (ECM) proteolysis which is important in metastasis....
Volume
17
Issue
2
Start Page
117
DOI
10.1016/j.jnutbio.2005.05.014
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Title
Phorbol-12-myristate acetate [PMA] mediated regulation of spermidine/spermine N-1 acetyltransferase expression in H-ras transformed fibroblasts
Source
Molecular Biology of the Cell
Date
2006
Author
Francis, E. J.; Hurta, R. A. R.
Genre
Journal Article
Volume
17
Issue
Suppl. S

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