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Title: Magnolol affects cellular proliferation, polyamine biosynthesis and catabolism-linked protein expression and associated cellular signaling pathways in human prostate cancer cells in vitro
Source: Functional Foods in Health and Disease
Date: 2015
Author: McKeown, Brendan T.; Hurta, Robert A. R.
Genre: Journal Article
Abstract: Background: Prostate cancer is the most commonly diagnosed form of cancer in men in Canada and the United States. Both genetic and environmental...
Volume: 5
Issue: 1
Start Page: 17




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Title: Ursolic acid mediated inhibition of human prostate cancer cell growth in vitro involves alterations in cell cycle related protein expression
Source: FASEB Journal
Date: 2015
Author: Hurta, Robert; Kim, Joseph; Catalli, Adriana; Neto, Catherine
Genre: Conference Abstract
Abstract: Ursolic acid is a constituent of the American cranberry (Vaccinium macrocarpon) and other Vaccinium fruit found primarily in the peel. In this...
Volume: 29
Issue: 1 Supplement
Start Page: 884.5



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Title: Magnolol affects cellular growth and proliferation in human prostate cancer cells in vitro
Date: 2015
Author: McKeown, Brendan Timothy
Genre: Dissertation/Thesis
Abstract: Prostate cancer is the most commonly diagnosed form of cancer in men in Canada and the United States. Both genetic and environmental factors...
Thesis Supervisor: Hurta, Robert
Publisher: University of Prince Edward Island
Publication Status: PUBLISHED




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Title: Lowbush blueberry component Pterostilbene inhibits the matrix metalloproteinase and the urokinase signaling systems in human prostate cancer cells via alterations in cellular signal transduction pathways
Source: FASEB Journal
Date: 2015
Author: Stetson, Colin
Genre: Conference Abstract
Volume: 29
Issue: 1
Start Page: 894.1




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Title: Magnolol affects expression of IGF-1 and associated binding proteins in human prostate cancer cells in vitro
Source: Anticancer Research
Date: 2014
Author: McKeown, Brendan T.; Hurta, Robert A. R.
Genre: Journal Article
Abstract: This study investigated the effects of magnolol, a compound from Magnolia officinalis, on the behavior of LNCaP and PC3 human prostate cancer cells...
Volume: 34
Issue: 11
Start Page: 6333




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Title: Flavonol-enriched fraction from Vaccinium macrocarpon fruit inhibits matrix metalloproteinase-2, matrix metalloproteinase-9 and urokinase-type plasminogen activator expression in human prostate cancer cells in vitro
Source: Functional Foods in Health and Disease
Date: 2014
Author: MacPhee, James; Stetson, Colin R.; Elwood, Benjamin W.; Patel, Kunal; McCallum, Jason; Neto, Catherine; Hurta, Robert A.R.
Genre: Journal Article
Abstract: Background: Prostate cancer, amongst other cancer types has a genetic and environmental component, which can contribute to prostate cancer...
Volume: 4
Issue: 11
Start Page: 474




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Title: Proanthocyanidins from the American cranberry (Vaccinium macrocarpon) induce cell cycle alterations in DU145 human prostate cancer cells in vitro by affecting the expression of cell cycle-associated proteins
Source: Functional Foods in Health and Disease
Date: 2014
Author: Kim, Joseph; McKeown, Brendan; Jahic, Haris; Patel, Kunal; Catalli, Adriana; Kulka, Marianna; Neto, Catherine; Hurta, Robert
Genre: Journal Article
Abstract: Background: Prostate cancer is one of the most common cancers in the world. There are genetic and environmental factors that can potentially impact...
Volume: 4
Issue: 4
Start Page: 130




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Title: Magnolol causes alterations in the cell cycle in androgen insensitive human prostate cancer cells in vitro by affecting expression of key cell cycle regulatory proteins
Source: Nutrition and Cancer
Date: 2014
Author: McKeown, Brendan T.; McDougall, Luke; Catalli, Adriana; Hurta, Robert A. R.
Genre: Journal Article
Abstract: Prostate cancer, one of the most common cancers in the Western world, affects many men worldwide. This study investigated the effects of magnolol,...
Volume: 66
Issue: 7
Start Page: 1154
DOI: 10.1080/01635581.2014.951736




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Title: American cranberry (Vaccinium macrocarpon) extract affects human prostate cancer cell growth via cell cycle arrest by modulating expression of cell cycle regulators
Source: Food & Function
Date: 2012
Author: Deziel, B.; MacPhee, J.; Patel, K.; Catalli, A.; Kulka, M.; Neto, C.; Gottschall-Pass, K.; Hurta, R.
Genre: Journal Article
Abstract: Prostate cancer is one of the most common cancers in the world, and its prevalence is expected to increase appreciably in the coming decades. As...
Volume: 3
Issue: 5
Start Page: 556
DOI: 10.1039/C2FO10145A




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Title: Ursolic acid and its esters: Occurrence in cranberries and other Vaccinium fruit and effects on matrix metalloproteinase activity in DU145 prostate tumor cells
Source: Journal of the Science of Food and Agriculture
Date: 2011
Author: Kondo, Miwako; MacKinnon, Shawna L; Craft, Cheryl C; Matchett, Michael D; Hurta, Robert A R; Neto, Catherine C
Genre: Journal Article
Volume: 91
Issue: 5
Start Page: 789
DOI: 10.1002/jsfa.4330



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Title: Alterations in the expression of cancer associated mediators in H-ras transformed murine fibroblast cells
Date: 2011
Author: Francis, Edward Joesph
Genre: Dissertation/Thesis
Abstract: The progression of cancer is characterized by the alteration in key cancer associated activities. This study investigates the expression of...
Thesis Supervisor: Hurta, Robert
ISBN: 9780494822494
Publisher: University of Prince Edward Island



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Title: Compounds of Vaccinium macrocarpon inhibit DU145 human prostate cancer cells
Date: 2011
Author: Scott, Bradley Edwin
Genre: Dissertation/Thesis
Abstract: Prostate cancer is the second most prevalent cancer in North American males. A series of in vitro studies were conducted to examine the effect of...
Thesis Supervisor: Hurta, Robert
ISBN: 9780494822562
Publisher: University of Prince Edward Island



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Title: The Effects of Cranberry Phytochemicals on the Behaviour of Prostate Cancer In Vitro and In Vivo
Date: 2011
Author: Deziel, Robert Andrew
Genre: Dissertation/Thesis
Abstract: With an estimated 24,600 cases, prostate cancer is one of the most prevalent cancers in Canada, and evidence suggests that the development of...
Thesis Supervisor: Hurta, Robert; Gottschall-Pass, Katherine
ISBN: 9780494822647
Publisher: University of Prince Edward Island




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Title: Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) inhibit matrix metalloproteinase-2 and matrix metalloproteinase-9 activity in human prostate cancer cells via alterations in multiple cellular signalling pathways
Source: Journal of Cellular Biochemistry
Date: 2010
Author: Deziel, Bob A.; Patel, Kunal; Neto, Catherine; Gottschall-Pass, Katherine; Hurta, Robert A. R.
Genre: Journal Article
Abstract: Prostate cancer is one of the most common cancers in the Western world, and it is believed that an individual's diet affects his risk of...
Volume: 111
Issue: 3
Start Page: 742
DOI: 10.1002/jcb.22761




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Title: Cranberry (Vaccinium macrocarpon) extract reduces tumour necrosis factor alpha-induced expression of cyclooxygenase-2 and inducible nitric oxide synthase in vascular smooth muscle cells
Source: FASEB Journal
Date: 2007
Author: MacDougall, Colleen; Amoroso, Jon; Neto, Catherine; Gottschall-Pass, Katherine; Hurta, Robert
Genre: Conference Abstract
Abstract: Natural 'bioactive' factors have the ability to attenuate atherogenesis in in vitro and in vivo models. The effects of cranberry on the...
Volume: 21
Issue: 5
Start Page: A249




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Title: Oncostatin M-mediated regulation of matrix metalloproteinases and associated mediators of MMPs' expression in H-ras transformed fibroblasts
Source: FASEB Journal
Date: 2007
Author: Francis, Edward Joseph; Hurta, Robert
Genre: Conference Abstract
Abstract: Oncostatin M (OSM) is a growth and differentiation factor which has been shown to exert both stimulatory and inhibitory effects on tissue invasion...
Volume: 21
Issue: 5
Start Page: A278




Bookmarks:

Title: Cranberry (Vaccinium macrocarpon) flavonoids inhibit matrix metalloproteinases (MMPs) in human prostate cancer cells
Source: FASEB Journal
Date: 2007
Author: MacLean, Malcolm Adam; Matchett, Michael David; Amoroso, Jon; Neto, Catherine; Hurta, Robert
Genre: Conference Abstract
Abstract: Blueberry (Vaccinium angustifolium) flavonoid-containing fractions have been shown to inhibit MMP activity (MMP-2/-9) in DU145 prostate cancer...
Volume: 21
Issue: 6
Start Page: A1000




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Title: MALDI-TOF MS characterization of proanthocyanidins from cranberry fruit (Vaccinium macrocarpon) that inhibit tumor cell growth and matrix metalloproteinase expression in vitro
Source: Journal of the Science of Food and Agriculture
Date: 2006
Author: Neto, C. C.; Krueger, C. G.; Lamoureaux, T. L.; Kondo, M.; Vaisberg, A. J.; Hurta, Robert A. R.; Curtis, S.; Matchett, M. D.; Yeung, H.; Sweeney-Nixon, Marva I.; Reed, J. D.
Genre: Journal Article
Abstract: Proanthocyanidin-rich extracts were prepared by fractionation of the fruit of the North American cranberry (Vaccinium macrocarpon). In vitro growth...
Volume: 86
Issue: 1
Start Page: 18




Bookmarks:

Title: Inhibition of matrix metalloproteinase activity in DU145 human prostate cancer cells by flavonoids from lowbush blueberry (Vaccinium angustifolium)
Subtitle: possible roles for protein kinase C and mitogen-activated protein-kinase-mediated events
Source: The Journal of Nutritional Biochemistry
Date: 2006
Author: Matchett, M. D.; MacKinnon, S. L.; Sweeney-Nixon, Marva I.; Gottschall-Pass, Katherine T.; Hurta, Robert A. R.
Genre: Journal Article
Abstract: Regulation of the matrix metalloproteinases (MMPs) is crucial to regulate extracellular matrix (ECM) proteolysis which is important in metastasis....
Volume: 17
Issue: 2
Start Page: 117
DOI: 10.1016/j.jnutbio.2005.05.014




Bookmarks:

Title: Phorbol-12-myristate acetate [PMA] mediated regulation of spermidine/spermine N-1 acetyltransferase expression in H-ras transformed fibroblasts
Source: Molecular Biology of the Cell
Date: 2006
Author: Francis, E. J.; Hurta, R. A. R.
Genre: Journal Article
Volume: 17
Issue: Suppl. S

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