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Title
Alterations to prepulse inhibition magnitude and latency in adult rats following neonatal treatment with domoic acid and social isolation rearing
Source
Behavioural Brain Research
Date
2016
Author
Marriott, Amber L.; Tasker, R. Andrew; Ryan, Catherine L.; Doucette, Tracy A.
Genre
Journal Article
Volume
298 Part B
Start Page
310
DOI
10.1016/j.bbr.2015.11.009
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Title
Alterations in caspase-3 in juvenile rats treated neonatally with domoic acid
Source
Journal of Behavioral and Brain Science
Date
2016
Author
Robbins, Mark A.; Ryan, Catherine L.; Doucette, Tracy A.
Genre
Journal Article
Volume
06
Issue
09
Start Page
357
DOI
10.4236/jbbs.2016.69034
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Title
Ischemic lesions localized to the medial prefrontal cortex produce selective deficits in measures of executive function in rats
Source
Behavioural Brain Research
Date
2015
Author
Deziel, Robert A.; Ryan, Catherine L.; Tasker, R. Andrew
Genre
Journal Article
Volume
293
Start Page
54
DOI
10.1016/j.bbr.2015.07.003
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Title
The performance of females on two mental rotation tasks
Subtitle
A possible mediating role of female hormones
Date
2015
Author
McIntosh, Emma
Genre
Honours
Abstract
Differences and similarities between the sexes has long been an area of curiosity and inquiry. Historically, research into sex differences in...
Publisher
University of Prince Edward Island
Publication Status
PUBLISHED
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Title
Neonatal domoic acid abolishes latent inhibition in male but not female rats and has differential interactions with social isolation.
Source
Neuroscience letters
Date
2014-08-22
Author
Marriott, Amber L; Tasker, R Andrew; Ryan, Catherine L; Doucette, Tracy A
Genre
Journal Article
Abstract
Deficits in attention have long been identified as a core feature in schizophrenia and related neuropsychiatric disorders. We have investigated the...
Volume
578
Start Page
22
DOI
10.1016/j.neulet.2014.06.025
ISSN
1872-7972
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Title
Neonatal domoic acid abolishes latent inhibition in male but not female rats and has differential interactions with social isolation
Source
Neuroscience Letters
Date
2014
Author
Marriott, Amber L. ; Tasker, R Andrew; Ryan, Catherine L.; Doucette, Tracy A.
Genre
Journal Article
Abstract
Deficits in attention have long been identified as a core feature in schizophrenia and related neuropsychiatric disorders. We have investigated the...
DOI
10.1016/j.neulet.2014.06.025
Full Text
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Title
Assessment of the face validity, construct validity, and etiological validity of a novel animal model of schizophrenia
Date
2013
Author
Robbins, Mark A.
Genre
Dissertation/Thesis
Abstract
Schizophrenia is a devastating neurological disorder that affects approximately 1% of the population and is characterized by positive, negative,...
Thesis Supervisor
Doucette, Tracey; Ryan, Catherine
Publisher
University of Prince Edward Island
Publication Status
PUBLISHED
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Title
Temporal memory dysfunction and alterations in Tyrosine hydroxylase immunoreactivity in adult rats following neonatal exposure to Domoic acid
Source
Neuroscience & Medicine
Date
2013
Author
Robbins, Mark A.; Ryan, Catherine L.; Marriott, Amber L.; Doucette, Tracy Ann
Genre
Journal Article
Abstract
The purpose of the present study was to determine whether early alterations in glutamate signaling, via daily injections of the glutamate agonist,...
Volume
04
Issue
01
Start Page
29
DOI
10.4236/nm.2013.41005
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Title
Neonatal domoic acid treatment produces alterations to prepulse inhibition and latent inhibition in adult rats
Source
Pharmacology, Biochemistry & Behavior
Date
2012
Author
Marriott, Amber L.; Ryan, Catherine L.; Doucette, Tracy A.
Genre
Journal Article
Abstract
Schizophrenia is a complex and severe mental disorder characterized by positive, negative and cognitive symptoms. Characteristic behavioral...
Volume
103
Issue
2
Start Page
338
DOI
10.1016/j.pbb.2012.08.022
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Title
Altered social interaction in adult rats following neonatal treatment with domoic acid
Source
Physiology & Behavior
Date
2011
Author
Ryan, Catherine L.; Robbins, Mark A.; Smith, Meghan T.; Gallant, Ian C.; Adams-Marriott, Amber L.; Doucette, Tracy A.
Genre
Journal Article
Abstract
Schizophrenia is a debilitating neurological disorder characterized by positive, negative, cognitive and/or emotional symptoms. Decreased social...
Volume
102
Issue
3-4
Start Page
291
DOI
10.1016/j.physbeh.2010.11.020
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Title
Neonatal exposure to low-dose domoic acid lowers seizure threshold in adult rats
Source
Neuroscience
Date
2010
Author
Gill, D. A.; Bastlund, J. F.; Watson, W. P.; Ryan, C. L.; Reynolds, D. S.; Tasker, R. A.
Genre
Journal Article
Abstract
Exposing Sprague–Dawley rat pups to very low, sub-convulsant doses of domoic acid (DOM) during perinatal development has been previously shown to...
Volume
169
Issue
4
Start Page
1789
DOI
10.1016/j.neuroscience.2010.06.045
Full Text
Bookmarks:
Title
Evaluations of behavior, neurochemistry, inflammation and cellular function in MPTP-induced models of Parkinson's disease: Effects of eicosapentaenoic acid (EPA) treatments
Date
2010
Author
Luchtman, Dirk Willem
Genre
Dissertation/Thesis
Abstract
Parkinson's disease (PD) is a progressive neurodegenerative disorder, characterized by motor and cognitive impairments. The neuropathological...
Thesis Supervisor
Song, Cai; Tasker, Andrew; Zidichouski, Jeffrey; Ryan, Catherine; Wang, Yanwen; Bate, Louis
ISBN
9780494644744
Publisher
University of Prince Edward Island
Full Text
Bookmarks:
Title
Neonatal low-dose domoic acid exposure during a critical period of central nervous system development: A potential animal model of schizophrenia
Date
2010
Author
Adams-Marriott, Amber L.
Genre
Dissertation/Thesis
Abstract
Schizophrenia is a complex and devastating mental disorder, found to affect up to 1% of the general population. Characterized by a variety of...
Thesis Supervisor
Doucette, Tracy; Ryan, Cathy
ISBN
9780494644645
Publisher
University of Prince Edward Island
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Title
Persistent changes in learning and memory in rats following neonatal treatment with domoic acid
Source
Physiology & Behavior
Date
2009
Author
Adams, A. L.; Doucette, Tracy A.; James, R.; Ryan, Catherine L.
Genre
Journal Article
Abstract
The present study examined the effects of neonatal exposure to serial low dose injections of the glutamate agonist, domoic acid (DOM), on learning...
Volume
96
Issue
4-5
Start Page
505
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Title
Effects of low dose neonatal domoic acid administration on behavioural and physiological response to mild stress in adult rats
Source
Physiology & Behavior
Date
2009
Author
Perry, M. A.; Ryan, C. L.; Tasker, R. A.
Genre
Journal Article
Abstract
Changes in glutamatergic signalling during neonatal development are known to result in long-lasting changes in brain function. Previous work in our...
Volume
98
Issue
1-2
Start Page
53
DOI
10.1016/j.physbeh.2009.04.009
Full Text
Bookmarks:
Title
Effectiveness of PSD95 inhibitors in permanent and transient focal ischemia in the rat
Source
Stroke: A Journal of Cerebral Circulation
Date
2008
Author
Sun, H. S.; Doucette, Tracy A.; Liu, Y.; Fang, Y.; Teves, L.; Aarts, M.; Ryan, Catherine L.; Bernard, P. B.; Lau, A.; Forder, J. P.; Salter, M. W.; Wang, Y. T.; Tasker, R. Andrew R.; Tymianski, M.
Genre
Journal Article
Abstract
Background and purpose:

Postsynaptic density-95 inhibitors reduce ischemic brain damage without inhibiting excitatory neurotransmission,...

Volume
39
Issue
9
Start Page
2544
Publication Status
NO_OBJ
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Bookmarks:
Title
Effects of estrous stage and time of day on prepulse inhibition in female rats
Source
Journal of Neuroscience Methods
Date
2008
Author
Adams, A. L.; Hudson, A.; Ryan, Catherine L.; Doucette, Tracy A.
Genre
Journal Article
Abstract
Prepulse inhibition (PPI) of the acoustic startle response is a measure of sensory motor gating, and is affected in various neuropsychiatric...
Volume
173
Issue
2
Start Page
295
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Title
Low dose domoic acid in neonatal rats abolishes nicotine induced conditioned place preference during late adolescence
Source
Amino Acids
Date
2008
Author
Burt, M. A.; Ryan, Catherine L.; Doucette, Tracy A.
Genre
Journal Article
Abstract
In this study, neonatal rats were chronically exposed to low, non-convulsive doses of the kainate receptor agonist domoic acid (DOM), or saline....
Volume
35
Issue
1
Start Page
247
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Bookmarks:
Title
Altered responses to novelty and drug reinforcement in adult rats treated neonatally with domoic acid
Source
Physiology & Behavior
Date
2008
Author
Burt, M. A.; Ryan, Catherine L.; Doucette, Tracy A.
Genre
Journal Article
Abstract
Activity in the mesocorticolimbic dopamine system is linked to responses to novelty, reward, and drug-seeking behaviours. Glutamate signaling,...
Volume
93
Issue
1-2
Start Page
327
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Bookmarks:
Title
Long-term efficacy of PSD-95 inhibitors in post-stroke treatment of ischemic brain damage
Source
Stroke
Date
2008
Author
Sun, H. S.; Doucette, Tracy A.; Liu, Y.; Aarts, M.; Ryan, Catherine L.; Bernard, P. B.; Lau, A.; Teves, L.; Salter, M. W.; Wang, Y.; Tasker, R. Andrew R.; Tymianski, M.
Genre
Journal Article
Start Page
13pages

Pages