Biography
Associate Professor
BSc (UPEI); PhD (McGill)
Dr. Barry Linkletter works to better understand and synthesize molecules that will interact and associate with four-stranded DNA, a novel DNA structure. These stabilizing molecules are candidates for drugs that regulate cell proliferation and may find a use in cancer therapy and genetic research.
Recent Publications
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Rapid hydrolysis of 2 ',3 '-cAMP with a Cu(II) complex
- Journal of the American Chemical Society, 1999
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Solid-phase synthesis of deoxynucleic guanidine (DNG) oligomers and melting point and circular dichroism analysis of binding fidelity of octameric thymidyl oligomers with DNA oligomers
- Journal of the American Chemical Society, 1999
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Synthesis of protected guanidinium linked dinucleoside incorporable into an oligonucleotide using solid phase DNA methodology
- Bioorganic & Medicinal Chemistry Letters, 1998
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Rapid hydrolysis of RNA with a CU-II complex
- Angewandte Chemie-International Edition in English, 1995
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Benzylchlorocarbene: UV absorption spectrum, kinetics for 1,2-H migration and mechanism for reaction with acetic acid as determined by combined continuous and laser-flash photolysis
- Laser Chemistry, 1990
Research Classification
- No classification given
Research Interests
- Molecular recognition of DNA secondary structures
- Telomeric DNA
- Solid-phase organic synthesis
- Novel nucleotide bases
Current Scholars in Chemistry
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