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Title: Interstitial detection of gold nanoparticles in deep tissues with optical radiance using porcine phantom
Source: Medical Imaging 2013. Biomedical Applications in Molecular, Structural, and Functional Imaging
Date: 2013
Author: Grabtchak, Serge; Tonkopi, Elena; Whelan, William M.
Genre: Book, Section
DOI: 10.1117/12.2008962
ISBN: 9780819494467

Title: Optical detection of gold nanoparticles in a prostate-shaped porcine phantom
Source: Journal of Biomedical Optics
Date: 2013
Author: Grabtchak, Serge; Tonkopi, Elena; Whelan, William M.
Genre: Journal Article
Volume: 18
Issue: 7
Start Page: 077005
DOI: 10.1117/1.JBO.18.7.077005

Title: Dynamic modeling of interstitial laser photocoagulation
Subtitle: implications for lesion formation in liver in vivo
Source: Lasers in Surgery and Medicine
Date: 1999
Author: Whelan, William M.; Wyman, D. R.
Genre: Journal Article
Abstract: Background and Objective: Interstitial Laser Photocoagulation (ILP) is a minimally invasive cancer treatment technique, whereby optical energy from...
Volume: 24
Issue: 3
Start Page: 202
DOI: 10.1002/(sici)1096-9101(1999)24:3<202::aid-lsm5>3.0.co;2-8

Title: Basic optothermal diffusion: theory for interstitial laser photocoagulation
Source: Medical Physics
Date: 1994
Author: Wyman, D. R.; Whelan, William M.
Genre: Journal Article
Volume: 21
Issue: 11
Start Page: 1651
DOI: 10.1118/1.597279

Title: Assessment of thermal coagulation in ex-vivo tissues using Raman spectroscopy
Source: Journal of Biomedical Optics
Date: 2010
Author: Rodrigues, Matthew; Weersink, Robert A.; Whelan, William M.
Genre: Journal Article
Abstract: Raman spectroscopy is used to study the effects of heating on specific molecular bonds present in albumen-based coagulation phantoms and ex-vivo...
Volume: 15
Issue: 6
Start Page: 068001

Title: Study of laser-induced thermoelastic deformation of native and coagulated ex-vivo bovine liver tissues for estimating their optical and thermomechanical properties
Source: Journal of Biomedical Optics
Date: 2010
Author: Soroushian, Behrouz; Whelan, William M.; Kolios, Michael C.
Genre: Journal Article
Volume: 15
Issue: 6
Start Page: 065002
DOI: 10.1117/1.3517455

Title: Spatially-resolved probing of biological phantoms by point-radiance spectroscopy
Source: Proc. of SPIE
Date: 2011
Author: Grabtchak, Serge; Palmer, Tyler J.; Whelan, William M.
Genre: Journal Article
Abstract: Interstitial fiber-optic based strategies for therapy monitoring and assessment rely on detecting treatment-induced changes in the light...
Volume: 7894
Issue: 78940A
DOI: 10.1117/12.874042

Title: Feasibility of interstitial near-infrared radiance spectroscopy platform for ex vivo canine prostate studies
Subtitle: Optical properties extraction, hemoglobin and water concentration, and gold nanoparticles detection
Source: Journal of Biomedical Optics
Date: 2014
Author: Grabtchak, Serge; Montgomery, Logan G.; Whelan, William M.
Genre: Journal Article
Abstract: The canine prostate is a close match for the human prostate and is used in research of prostate cancers. Determining accurately optical absorption...
Volume: 19
Issue: 5
Start Page: 057003
DOI: 10.1117/1.JBO.19.5.057003

Title: Spectro-angular mapping of localized gold inclusions in Intralipid phantoms
Source: Proc. SPIE 8427, Biophotonics
Date: 2012
Author: Grabtchak, Serge; Palmer, Tyler J.; Whelan, William M.
Genre: Journal Article
Abstract: We have applied an interstitial radiance-based technique based on a spectro-angular mapping approach to the identification and angular localization...
Volume: 8427
Start Page: 84271R
DOI: 10.1117/12.927986

Title: Perturbative diffusion theory formalism for interpreting temporal light intensity changes during laser interstitial thermal therapy
Source: Physics in Medicine and Biology
Date: 2007
Author: Chin, Lee C. L.; Whelan, William M.; Vitkin, I. Alex
Genre: Journal Article
Abstract: In an effort to understand dynamic optical changes during laser interstitial thermal therapy ( LITT), we utilize the perturbative solution of the...
Volume: 52
Issue: 6
Start Page: 1659
DOI: 10.1088/0031-9155/52/6/008

Title: Dynamics of laser induced thermoelastic expansion of native and coagulated ex-vivo soft tissue samples and their optical and thermo-mechanical properties
Source: Photons Plus Ultrasound: Imaging and Sensing 2011
Date: 2011
Author: Soroushian, Behrouz ; Whelan, William M. ; Kolios, Michael C.
Genre: Conference Proceedings
Abstract: The interferometric measurement of laser induced thermoelastic expansion of tissue samples can be used to estimate their optical, thermal and...
Volume: 7899
Issue: 78990Z
DOI: 10.1117/12.876011

Title: Optical absorption and scattering properties of bulk porcine muscle phantoms from interstitial radiance measurements in 650–900 nm range
Source: Physics in Medicine & Biology
Date: 2014
Author: Grabtchak, Serge; Montgomery, Logan G. ; Whelan, William M.
Genre: Journal Article
Abstract: We demonstrated the application of relative radiance-based continuous wave (cw) measurements for recovering absorption and scattering properties ...
Volume: 59
Issue: 10
Start Page: 2431
DOI: 10.1088/0031-9155/59/10/2431

Title: Radiance spectroscopy tool box for characterizing Au Nanoparticles in tissue mimicking phantoms as applied to prostate
Source: Journal of Cancer Science and Therapy
Date: 2011
Author: Grabtchak, Gerge; Palmer, Tyler J.; Whelan, William M.
Genre: Journal Article
Abstract: Background: We have developed a new approach to map localized inclusions of gold nanoparticles in the Intralipid-1% liquid phantom. Our goal was to...
Volume: 3
Issue: S1-008
DOI: 10.4172/1948-5956.S1-008

Title: Models and measurements of light intensity changes during laser interstitial thermal therapy
Subtitle: implications for optical monitoring of the coagulation boundary location
Source: Physics in Medicine and Biology
Date: 2003
Author: Chin, L. C. L.; Whelan, William M.; Vitkin, I. A.
Genre: Journal Article
Abstract: We have developed a multi-region spherical Monte Carlo (MC) model to simulate the dynamic changes in light intensity measured during laser...
Volume: 48
Issue: 4
Start Page: 543

Title: Information content of point radiance measurements in turbid media
Subtitle: implications for interstitial optical property quantification
Source: Applied Optics
Date: 2006
Author: Chin, L. C. L.; Whelan, William M.; Vitkin, I. A.
Genre: Journal Article
Abstract: Motivated by a recent report by Dickey et al. [Phys. Med. Biol. 46, 2359 (2001)], who demonstrated optical property retrieval by using relative...
Volume: 45
Issue: 9
Start Page: 2101
DOI: 10.1364/ao.45.002101